SUSCEPTIBILITIES OF SALMONELLA TYPHI AND OTHER BACTERIAL PATHOGENS TO ANTIBIOTICS AND HOT AQUEOUS EXTRACT OF HIBISCUS SABDARIFFA
ABSTRACT
The susceptibilities of Salmonella typhi and other pathogens to antibiotics and hot aqueous extract ofHibiscus sabdariffawere investigated using agar diffusion and agar well diffusion methods respectively.Salmonella typhiwas sensitive to ampicillin, cetriaxone, ciprofloxacin, gentamycin of ofloxacin and perfloxacin. Nitrofurantoin, ampicillin, clarithomycin and augumentin are resistant.Escherichia coli, Klebsiella spp,andStaphylococcus aureuswere sensitive to 50%, 70% and 60% of the antibiotics respectively.Pseudomonas aeruginosawas resistant to all antibiotics.Hibiscus sabdariffaextract (0.6g in 6ml of sterile distilled water) was active againstS. typhiat concentrations of 100mg/ml, 50mg/ml and 25mg/ml (inhibitions zone diameter IZDs = 23mm, 20mm and 16mm respectively).Staphylococcus aureuswas susceptible to 100mg/ml, 50mg/ml, 25mg/ml and 12.5mg/ml of the extract with IZDs of 29mm, 18mm, 17mm and 14mm respectively.Klebsiella sppwas susceptible to concentrations of 25mg/ml and 12.5mg/ml of the extract with IZDs of 15mm and 10mm respectively.Escherichia coliandPseudomonasaeruginosawere resistant to all the concentrations ofH. sabdariffaextract. It is therefore imperative to note that the use of medicinal plants is recommended to the Government and Industry.
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